NOVA (Semax) and SYNC (Selank) share an origin — both derived from research peptide programs studying central nervous system mechanisms — but act on opposite sides of neural activation. Semax research focuses on BDNF/NGF upregulation and dopaminergic activation; Selank on GABA-A modulation and anxiolytic activity without sedation. Published studies have directly compared their mechanisms. The pairing targets both neuroprotection and nervous system regulation.

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